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Molecular Pathology

The MAWD Molecular Lab was established in 2010 under the direction of Dr. Samuel Caughron, the region's first board certified Molecular Genetic Pathologist. The molecular diagnostics team also includes Pradip Manna, PhD, and Dr. Jon Thomason. Our molecular lab brings the latest advances in diagnostics and personalized medicine to Kansas City and has been designed from the ground up with a vision of the future. The MAWD Molecular Lab houses state-of-the-art molecular equipment capable of running the most advanced diagnostics assays. The lab is staffed by experts in molecular techniques, and is continually adding to the menu of tests performed.

 

Our growing test menu currently offers:

Oncology

  • Breast Cancer

    • HER2 Amplification by FISH

  • Colorectal Cancer

    • KRAS Mutation Analysis

    • BRAF Mutation Analysis

    • NRAS Mutation Analysis

    • Microsatellite Instability (MSI) Analysis

    • Mismatch Repair (MMR) Gene Expression by IHC

  • Lung Cancer

    • EGFR Mutation Analysis

    • ALK Translocation Detection by FISH

    • KRAS Mutation Analysis

    • ROS1 by FISH

    • BRAF Mutation Analysis

  • Skin Cancer

    • BRAF for Melanoma

  • Melanoma

    • BRAF Mutation Analysis

  • Oncomine Focus Next Generation Sequencing (NGS) Assay

    • 52 Gene Targeted NGS Assay

  • BRCA 1/2 NGS for Somatic Mutation Analysis

    • Full gene sequencing for somatic mutation analysis

Women's Health

  • High-risk HPV DNA analysis using the Cobas® HPV test by Roche Diagnostics

  • High-risk HPV RNA analysis using the Aptima Panther test by Hologic

  • HPV DNA 16/18 genotyping DNA by Roche Diagnostics

  • HPV RNA 16 and 18/45 RNA by Hologic

  • Roche Cobas Chlamydia trachomatis (CT) detection by RT-PCR (DNA)

  • Roche Cobas Neisseria gonorrhoeae (NG) detection by RT-PCR (DNA)

  • Hologic Aptima Chlamydia trachomatis (CT) detection by Target Mediated Amplification (TMA)

  • Hologic Aptima Neisseria gonorrhoeae (NG) detection by Target Mediated Amplification (TMA)

  • Trichomonas vaginalis (TV) detection by RT-PCR

  • Herpes HSV 1 & HSV 2 detection by RT-PCR

  • Group B Streptococcus detection by PCR

  • Aptima Vaginal Panel (performed on the Hologic Panther)

    • Lactobacillus spp. (L. gasseri, L. crispatus, and L. jensenii)

    • Gardnerella vaginalis

    • Atopobium vaginae

    • Candida spp. (C. albicans, C. tropicalis, C. parapsilosis, and C. dubliniensis)

    • Candida glabrata

    • Trichomonas vaginalis

  • BD MAX Vaginal Panel

    • Lactobacillus spp. (L. crispatus and L. jensenii)

    • Gardnerella vaginalis

    • Atopobium vaginae

    • Bacterial Vaginosis Associated Bacteria-2 (BVAB-2)

    • Megasphaera-1

    • Candida spp. (C. albicans, C. tropicalis, C. parapsilosis, and C. dubliniensis)

    • Candida glabrata

    • Candida krusei

    • Trichomonas vaginalis

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