Test Directory

Increased polyclonal IgM levels are found in viral, bacterial, and parasitic infections, liver diseases, rheumatoid arthritis, scleroderma, cystic fibrosis and heroin addiction. Monoclonal IgM is increased in Waldenström’s macroglobulinemia. Increased loss of IgM is found in protein‑losing enteropathies and in burns. Decreased synthesis of IgM occurs in congenital and acquired immunodeficiency syndromes.