Increased polyclonal IgM levels are found in viral, bacterial, and parasitic infections, liver diseases, rheumatoid arthritis, scleroderma, cystic fibrosis and heroin addiction. Monoclonal IgM is increased in Waldenström’s macroglobulinemia. Increased loss of IgM is found in protein‑losing enteropathies and in burns. Decreased synthesis of IgM occurs in congenital and acquired immunodeficiency syndromes.
As with other turbidimetric or nephelometric procedures, this test may not provide accurate results in patients with monoclonal gammopathy, due to individual sample characteristics which can be assessed by electrophoresis.18
Room temperature: 2 months Refrigerated: 4 months Frozen: 6 months
IgM Quant; IgM, Serum; Quantitative IgM, Serum; Immunoglobin M, quantitiative
Serum, gel separator, SST
0 - 999
40 - 230